Modeling Intracerebral Hemorrhage Growth and Response to Anticoagulation
نویسندگان
چکیده
منابع مشابه
Modeling Intracerebral Hemorrhage Growth and Response to Anticoagulation
The mechanism for hemorrhage enlargement in the brain, a key determinant of patient outcome following hemorrhagic stroke, is unknown. We performed computer-based stochastic simulation of one proposed mechanism, in which hemorrhages grow in "domino" fashion via secondary shearing of neighboring vessel segments. Hemorrhages were simulated by creating an initial site of primary bleeding and an ass...
متن کاملEmergency reversal of anticoagulation after intracerebral hemorrhage.
BACKGROUND AND PURPOSE Although intracerebral hemorrhage is one of the most serious complications during oral anticoagulant therapy, there are no guidelines on emergency treatment with respect to reversal of anticoagulation effect in these patients. METHODS We retrospectively compared laboratory data and clinical features in 17 cases of anticoagulant-related intracerebral hemorrhage treated w...
متن کاملAcute Management of Anticoagulation-Associated Intracerebral Hemorrhage
One of the most serious forms of stroke is intracerebral hemorrhage (ICH) as fewer than 30 % of patients recover to functional independence and the one-year mortality rate of over 50 % is very high [1–3]. In hemorrhagic stroke, oral anticoagulation-associated intracerebral hemorrhage (OAC-ICH) is of particular concern because it is associated with larger hemorrhage volumes, increased ventricula...
متن کاملShould anticoagulation be resumed after intracerebral hemorrhage?
Intracerebral hemorrhage (ICH) is the most feared and the most deadly complication of oral anticoagulant therapy, eg, with warfarin (Coumadin). After such an event, clinicians wonder whether their patients should resume anticoagulant therapy. The authors review the management of anticoagulation during and after anticoagulation-associated ICH.
متن کاملHypothesis of intracerebral hemorrhage growth.
Hemorrhage Growth To the Editor: I read with great interest the article by Mayer reviewing ultra-early hemostatic therapy for intracerebral hemorrhage (ICH).1 Prospective and retrospective studies had confirmed that ICH growth is a common phenomenon, especially within the first 6 hours of onset. Moreover, hematoma volume has been identified as the single most powerful predictor of 30-day mortal...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0048458